Ziana Gel (.025% Tretinoin, 1.2% Clindamycin)
Gel 30g and 60g tubes
Ziana Gel became available in 2006 and is produced by the Medicis Pharmaceutical Corporation. Ziana Gel combines two well established and widely used acne treatments in an easy to administer combination product. This offers the demonstrated efficacy and safety of topical tretinoin and clindamycin, with the convenience and cost effectiveness of a single product. Ziana is an aqueous based gel formulation with no alcohol.
Ziana gel should be adminstered once daily, at bedtime. At each administration, patients should squeeze a pea sized amount of medication onto one fingertip, dot it onto the chin, cheeks, nose, and forehead, then gently rub the medication over the entire face.
No single adverse event was reported by more than 4% of subjects taking Ziana Gel. The incidence of adverse reactions with Ziana gel was not substantially higher than the incidence of the same events in patients who received tretinoin, clindamycin, or a vehicle alone. Ziana had a dry skin rate of only 1% in the clinical trials as not by product labeling.
Off Label Use: Some forms of this medication are used to improve the appearance of the skin and minimize fine line wrinkles. This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional. Your doctor may also use this medication to treat other conditions.
Other available branded topical tretinoin products and topical retinoid products include:
- Retin-A Micro